ADPKD
DISCLAIMER: This is an archive page describing a task force from the precursor project PARENCHIMA. The content is not up to date
MRI IN ADPKD
Despite total kidney volume (TKV) having been approved as a prognostic enrichment biomarker, it has not been approved as outcome biomarker, yet, and additional evidence is required. Moreover, MRI offers a wide spectrum of microstructural/functional biomarkers which still needs to be investigated and validated in ADPKD.
This task force provides a central contact point for researchers with an interest in MRI for applications in Autosomal Dominant Polycystic Kidney Disease (ADPKD). The task force aims to improve the sharing of resources but will also aim to set up collaborative projects and prospective clinical studies in ADPKD involving MRI of the kidney.
Main aims:
- Share expertise between the individual groups involved Apply for grant funding to further validate MRI biomarkers in ADPKD
- Provide additional evidence for TKV as possible outcome biomarker
- Go beyond TKV and investigate multiparametric MRI potential in ADPKD Explore the possibility for multiparametric multicentre/collaborative studies
Recent advances
Synergy with other PKD consortia
- US PKD Outcome Consortium (PKDOC): on February 8th 2019 the task force presented its activities to PKDOC, during its monthly TC. If interested you can download the presentation here.
- CYSTic - An international consortium to build a longitudinal observational cohort of patients with ADPKD Chief investigator: Prof. Albert Ong (University of Sheffield, UK) Multinational initiative (UK, Belgium, Germany, the Netherlands, France, Italy, Czech Republic, Spain)
Groups involved
| Center
|
People involved
|
Expertise
|
|---|---|---|
| Medical University of Vienna, Austria
|
Marcos Wolf
|
Radiology
|
| Universitair Ziekenhuis Brussel, Belgium
|
Patricia van der Niepen
|
Nephrology
|
| Institute for Clinical and Experimental Medicine, Prague, Czech Republic
|
Janka Slatinska
|
Nephrology
|
| Aarhus University Hospital, Denmark
|
Jens Dam Jensen, Christoffer Lautsen
|
Nephrology, Medical Imaging
|
| Centre Hospitalier Universitaire (CHU) de Bordeaux, France
|
Nicolas Grenier
|
Radiology
|
| Charitè - Universitätsmedizin Berlin, Germany
|
Kai-Uwe Eckardt, Christian Rosenberger
|
Nephrology, Radiology
|
| Heinrich-Heine-Universität Düsseldorf, Germany
|
Alexandra Ljimani
|
Radiology
|
| Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
|
Andrea Remuzzi, Anna Caroli, Norberto Perico, Giuseppe Remuzzi
|
MR imaging, Nephrology
|
| Sapienza University, Rome, Italy
|
Silvia Lai, Sandro Mazzaferro, Anna Rita D’Angelo, Daniele Mastroluca, Marco Mangiulli
|
Nephrology
|
| Private Health Institution- “Dr.Adamovski”, Bitola, Macedonia
|
Pavle Adamovski
|
Medicine
|
| Haukeland University Hospital, Bergen, Norway
|
Eli Eikefjord
|
Radiography
|
| Clinical Center of Vojvodina, Novi sad, Serbia
|
Olivera Nikolic
|
Radiology
|
| Lausanne University Hospital, Switzerland
|
Olivier Bonny
|
Nephrology
|
| Geneve University Hospital, Switzerland
|
Jean-Paul Vallee, Lena Berchtold
|
Radiology, Nephrology
|
| University Medical Centre Utrecht, the Netherlands
|
Peter Blankestijn
|
Nephrology
|
| University of Sheffield, UK
|
Albert Ong, Rosylin Simms
|
Nephrology
|
| Uppsala University Hospital, Sweden | Per Liss | Radiology |
| UCL London, UK
|
Fabio Nery, Isky Gordon
|
MR physics, Radiology
|
Task force leads
Lead: Prof. Andrea Remuzzi Vice-lead: Prof. Albert Ong
| Members | ||
|---|---|---|
| Pavle Adamovski | Dr. Lena Berchtold | Prof. Peter Blankestijn |
| Dr. Olivier Bonny | Dr. Peter Boor | Dr. Anna Caroli |
| Prof. Laustsen Christoffer | Prof. Anna Rita D’Angelo | Prof. Dr. Kai-Uwe Eckardt |
| Eli Eikefjord | Prof. Isky Gordon | Prof. Nicolas Grenier |
| Dr. Jens Dam Jensen | Prof. Silvia Lai | Dr. Per Liss |
| Dr. Alexandra Ljimani | Dr. Marco Mangiulli | Dr. Daniela Mastroluca |
| Prof. Sandro Mazzaferro | Dr. Fabio Nery | Prof. Dr. Olivera Nikolic |
| Prof. Albert Ong | Dr. Norberto Perico | Dr. Christian Rosenberg |
| Dr. Rosylin Simms | Dr. Janka Slatinská | Prof. Jean Paul Vallee |
| Dr. Marcos Wolf | Dr. Patricia van der Niepen |