Working group 3 joins up clinical sites working on renal MRI, and will pave the way for clinical use of renal MRI by addressing the need for stronger evidence in patients.
The standardised methods developed in WG1 and WG2 will be used in large prospective multicentre clinical studies aimed at providing additional evidence of biological and clinical validity (against histopathology and reference methods) and clinical utility (prognostic value) of MRI biomarkers in renal disease.
Prepare the ground for a large scale longitudinal multicentre study aimed at providing additional evidence of biological and clinical validity of MRI biomarkers in CKD (look for fundings, draw up minimum standards for sites to participate in multicentre trials)
Secure grant funding to further validate MRI biomarkers in ADPKD
Secure grant funding to validate MRI biomarkers in renal transplantation
Coordinate smaller scale studies on specific relevant disease areas
Add MRI to ongoing renal initiative
Create a study documentation repository, containing study documentation from past/ongoing clinical studies involving renal MRI, which could be helpful for designing new study protocols
Publication of an open access special issue on MRI biomarkers in renal disease in the journal Nephrol Dial Transplant, including an editorial, a position paper and 4 review papers (ASL, BOLD, DWI, T1&T2 mapping) providing a picture of the state of the art and practical recommendations. The special issue is free to view and download.
Creation of an ADPKD task force ( task force page), joining together all WG3 participants actively working in ADPKD MRI, aimed at securing grant funding to further validate MRI biomarkers in ADPKD.
Creation of a renal transplantation task force ( task force page), joining together all WG3 participants actively working in MRI in renal transplantation, aimed at securing grant funding to further validate MRI biomarkers in renal transplantation.
April 23rd 2018, Utrecht, The Netherlands - WG3 strategy meeting (meeting page)
October 13th 2017, Berlin, Germany - WG3 yearly meeting (meeting page)
July 13-14th 2017, Bergamo, Italy - WG3 kick-off meeting (meeting page)
If you need additional information, or in case you are interested in joining this effort, please contact the WG3 leads:
Anna Caroli (contact)
Nicholas Selby (contact)
Working group 3 Lead: Dr Anna Caroli
Working group 3 Vice-Lead: Dr Nicholas Selby