This task force joins together all WG3 participants actively working in ADPKD MRI.
Despite total kidney volume (TKV) having been approved as a prognostic enrichment biomarker, it has not been approved as outcome biomarker, yet, and additional evidence is required.
Moreover, MRI offers a wide spectrum of microstructural/functional biomarkers which still needs to be investigated and validated in ADPKD.
Main aims:
- Share expertise between the individual groups involved
- Apply for grant funding to further validate MRI biomarkers in ADPKD
- Provide additional evidence for TKV as possible outcome biomarker
- Go beyond TKV and investigate multiparametric MRI potential in ADPKD - Explore the possibility for multiparametric multicentre/collaborative studies
Recent advances
- Synergy with other PKD consortia
- US PKD Outcome Consortium (PKDOC): on February 8th 2019 the task force presented its activities to PKDOC, during its monthly TC. If interested you can download the presentation here.
- CYSTic - An international consortium to build a longitudinal observational cohort of patients with ADPKD
Chief investigator: Prof. Albert Ong (University of Sheffield, UK)
Multinational initiative (UK, Belgium, Germany, the Netherlands, France, Italy, Czech Republic, Spain)
Task force leads
- Lead: Prof. Andrea Remuzzi
- Vice-lead: Prof. Albert Ong
Groups involved
| Center
|
People involved
|
Expertise
|
|---|---|---|
| Medical University of Vienna, Austria
|
Marcos Wolf
|
Radiology
|
| Universitair Ziekenhuis Brussel, Belgium
|
Patricia van der Niepen
|
Nephrology
|
| Institute for Clinical and Experimental Medicine, Prague, Czech Republic
|
Janka Slatinska
|
Nephrology
|
| Aarhus University Hospital, Denmark
|
Jens Dam Jensen, Christoffer Lautsen
|
Nephrology, Medical Imaging
|
| Centre Hospitalier Universitaire (CHU) de Bordeaux, France
|
Nicolas Grenier
|
Radiology
|
| Charitè - Universitätsmedizin Berlin, Germany
|
Kai-Uwe Eckardt, Christian Rosenberger
|
Nephrology, Radiology
|
| Heinrich-Heine-Universität Düsseldorf, Germany
|
Alexandra Ljimani
|
Radiology
|
| Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
|
Andrea Remuzzi, Anna Caroli, Norberto Perico, Giuseppe Remuzzi
|
MR imaging, Nephrology
|
| Sapienza University, Rome, Italy
|
Silvia Lai, Sandro Mazzaferro, Anna Rita D’Angelo, Daniele Mastroluca, Marco Mangiulli
|
Nephrology
|
| Private Health Institution- “Dr.Adamovski”, Bitola, Macedonia
|
Pavle Adamovski
|
Medicine
|
| Haukeland University Hospital, Bergen, Norway
|
Eli Eikefjord
|
Radiography
|
| Clinical Center of Vojvodina, Novi sad, Serbia
|
Olivera Nikolic
|
Radiology
|
| Lausanne University Hospital, Switzerland
|
Olivier Bonny
|
Nephrology
|
| Geneve University Hospital, Switzerland
|
Jean-Paul Vallee, Lena Berchtold
|
Radiology, Nephrology
|
| University Medical Centre Utrecht, the Netherlands
|
Peter Blankestijn
|
Nephrology
|
| University of Sheffield, UK
|
Albert Ong, Rosylin Simms
|
Nephrology
|
| Uppsala University Hospital, Sweden | Per Liss | Radiology |
| UCL London, UK
|
Fabio Nery, Isky Gordon
|
MR physics, Radiology
|
