This task force joins together all WG3 participants actively working in ADPKD MRI.

Despite total kidney volume (TKV) having been approved as a prognostic enrichment biomarker, it has not been approved as outcome biomarker, yet, and additional evidence is required.

Moreover, MRI offers a wide spectrum of microstructural/functional biomarkers which still needs to be investigated and validated in ADPKD.

Main aims:

  • Share expertise between the individual groups involved
  • Apply for grant funding to further validate MRI biomarkers in ADPKD
    - Provide additional evidence for TKV as possible outcome biomarker
    - Go beyond TKV and investigate multiparametric MRI potential in ADPKD
  • Explore the possibility for multiparametric multicentre/collaborative studies

Recent advances

  • Synergy with other PKD consortia
    - US PKD Outcome Consortium (PKDOC): on February 8th 2019 the task force presented its activities to PKDOC, during its monthly TC. If interested you can download the presentation here.
    - CYSTic - An international consortium to build a longitudinal observational cohort of patients with ADPKD
    Chief investigator: Prof. Albert Ong (University of Sheffield, UK)
    Multinational initiative (UK, Belgium, Germany, the Netherlands, France, Italy, Czech Republic, Spain)

Task force leads

Groups involved

People involved
Medical University of Vienna, Austria
Marcos Wolf
Universitair Ziekenhuis Brussel, Belgium
Patricia van der Niepen
Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Janka Slatinska
Aarhus University Hospital, Denmark
Jens Dam Jensen, Christoffer Lautsen
Nephrology, Medical Imaging
Centre Hospitalier Universitaire (CHU) de Bordeaux, France
Nicolas Grenier
Charitè - Universitätsmedizin Berlin, Germany
Kai-Uwe Eckardt, Christian Rosenberger
Nephrology, Radiology
Heinrich-Heine-Universität Düsseldorf, Germany
Alexandra Ljimani
Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
Andrea Remuzzi, Anna Caroli, Norberto Perico, Giuseppe Remuzzi
MR imaging, Nephrology
Sapienza University, Rome, Italy
Silvia Lai, Sandro Mazzaferro, Anna Rita D’Angelo, Daniele Mastroluca, Marco Mangiulli
Private Health Institution- “Dr.Adamovski”, Bitola, Macedonia
Pavle Adamovski
Haukeland University Hospital, Bergen, Norway
Eli Eikefjord
Clinical Center of Vojvodina, Novi sad, Serbia
Olivera Nikolic
Lausanne University Hospital, Switzerland
Olivier Bonny
Geneve University Hospital, Switzerland
Jean-Paul Vallee, Lena Berchtold
Radiology, Nephrology
University Medical Centre Utrecht, the Netherlands
Peter Blankestijn
University of Sheffield, UK
Albert Ong, Rosylin Simms
Uppsala University Hospital, Sweden Per Liss Radiology
UCL London, UK
Fabio Nery, Isky Gordon
MR physics, Radiology